Peri‐ictal magnetic resonance imaging characteristics in dogs with suspected idiopathic epilepsy

Background The pathophysiology of changes in magnetic resonance imaging (MRI) detected after a seizure is not fully understood. Objective To characterize and describe seizure-induced by MRI. Animals Eighty-one client-owned dogs diagnosed with idiopathic epilepsy. Methods Data collected retrospectively from medical records included anatomical areas affected, T1-, T2-weighted T2-FLAIR (fluid-attenuated inversion recovery) appearance, whether were unilateral or bilateral, symmetry, contrast enhancement, mass effect, and, gray white matter distribution. Diffusion- perfusion weighted maps evaluated, if available. Results Seizure-induced T2-hyperintense no suppression signal on FLAIR. Lesions T1-isointense (55/81) hypointense (26/81), local effect (23/81) enhancement (12/81). majority bilateral (71/81) symmetrical (69/71). most common affected the hippocampus (39/81) cingulate gyrus (33/81), piriform lobes (32/81). Distribution analysis suggested concurrence between pulvinar thalamic nuclei, parahippocampal gyrus, lobe, gyrus. Diffusion (DWI) characteristics mixed-pattern restricted, facilitated, normal diffusion. Perfusion (PWI) showed either hypoperfusion (6/9) hyperperfusion (3/9). Conclusions Clinical Importance More areas, than previously reported, have been identified that could incur changes. Similar to human literature, DWI PWI reflect underlying metabolic vascular